Department of Molecular Genetics and Cell Biology
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Regulation of G2/M progression by the STE mitogen-activated protein kinase pathway in budding yeast filamentous growth.
Molecular biology of the cell Oct, 1999 | Pubmed ID: 10512868
Role of oxidative phosphorylation in Bax toxicity.
Molecular and cellular biology May, 2000 | Pubmed ID: 10779348
Enhanced cell polarity in mutants of the budding yeast cyclin-dependent kinase Cdc28p.
Molecular biology of the cell Nov, 2001 | Pubmed ID: 11694591
Marker-fusion PCR for one-step mutagenesis of essential genes in yeast.
Yeast (Chichester, England) Jan, 2002 | Pubmed ID: 11788969
Peptide chips for the quantitative evaluation of protein kinase activity.
Nature biotechnology Mar, 2002 | Pubmed ID: 11875428
Sensing, signalling and integrating physical processes during Saccharomyces cerevisiae invasive and filamentous growth.
Microbiology (Reading, England) Apr, 2002 | Pubmed ID: 11932437
Robust G1 checkpoint arrest in budding yeast: dependence on DNA damage signaling and repair.
Journal of cell science Apr, 2002 | Pubmed ID: 11950891
Digital time-lapse microscopy of yeast cell growth.
Methods in enzymology , 2002 | Pubmed ID: 12073352
Bcl-x(L) complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12244097
An essential function of yeast cyclin-dependent kinase Cdc28 maintains chromosome stability.
The Journal of biological chemistry Dec, 2002 | Pubmed ID: 12359726
NuA4 subunit Yng2 function in intra-S-phase DNA damage response.
Molecular and cellular biology Dec, 2002 | Pubmed ID: 12417725
Design and implementation of algorithms for focus automation in digital imaging time-lapse microscopy.
Cytometry Dec, 2002 | Pubmed ID: 12454979
Asynchronous cell cycle and asymmetric vacuolar inheritance in true hyphae of Candida albicans.
Eukaryotic cell Jun, 2003 | Pubmed ID: 12796285
Histone H2AX phosphorylation as a predictor of radiosensitivity and target for radiotherapy.
The Journal of biological chemistry Jan, 2004 | Pubmed ID: 14561744
Monitoring changes in the subcellular location of proteins in S. cerevisiae.
Methods in molecular biology (Clifton, N.J.) , 2004 | Pubmed ID: 14970663
Relevance and irrelevance of DNA damage response to radiotherapy.
DNA repair Aug-Sep, 2004 | Pubmed ID: 15279813
Yeast cell death during DNA damage arrest is independent of caspase or reactive oxygen species.
The Journal of cell biology Aug, 2004 | Pubmed ID: 15289493
Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.
Molecular and cellular biology Oct, 2005 | Pubmed ID: 16166626
Optimizing thiophosphorylation in the presence of competing phosphorylation with MALDI-TOF-MS detection.
Journal of proteome research Sep-Oct, 2005 | Pubmed ID: 16212443
Assaying Bcr-Abl kinase activity and inhibition in whole cell extracts by phosphorylation of substrates immobilized on agarose beads.
Analytical biochemistry Dec, 2005 | Pubmed ID: 16236241
Control of the yeast cell cycle with a photocleavable alpha-factor analogue.
Angewandte Chemie (International ed. in English) Sep, 2006 | Pubmed ID: 16937420
Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2006 | Pubmed ID: 16940359
Photocleavable peptide hydrogel arrays for MALDI-TOF analysis of kinase activity.
The Analyst Oct, 2006 | Pubmed ID: 17003856
Non-catalytic function for ATR in the checkpoint response.
Cell cycle (Georgetown, Tex.) Aug, 2007 | Pubmed ID: 17721080
Investigating quantitation of phosphorylation using MALDI-TOF mass spectrometry.
Journal of mass spectrometry : JMS Apr, 2008 | Pubmed ID: 18064576
A solid-phase Bcr-Abl kinase assay in 96-well hydrogel plates.
Analytical biochemistry Apr, 2008 | Pubmed ID: 18194660
Phosphoprotein profiling by PA-GeLC-MS/MS.
Journal of proteome research Jul, 2008 | Pubmed ID: 18510356
Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide.
Nature chemical biology Jul, 2008 | Pubmed ID: 18516048
Rapid validation of Mascot search results via stable isotope labeling, pair picking, and deconvolution of fragmentation patterns.
Molecular & cellular proteomics : MCP Aug, 2009 | Pubmed ID: 19435713
Morphogenesis signaling components influence cell cycle regulation by cyclin dependent kinase.
Cell division Jul, 2009 | Pubmed ID: 19566963
A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1.
Gene Nov, 2009 | Pubmed ID: 19647054
Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping.
DNA repair Dec, 2009 | Pubmed ID: 19880356
Cell treatment and lysis in 96-well filter-bottom plates for screening Bcr-Abl activity and inhibition in whole-cell extracts.
Journal of biomolecular screening Apr, 2010 | Pubmed ID: 20237206
A bead-based activity screen for small-molecule inhibitors of signal transduction in chronic myelogenous leukemia cells.
Molecular cancer therapeutics May, 2010 | Pubmed ID: 20423990
Peptide reporters of kinase activity in whole cell lysates.
Biopolymers , 2010 | Pubmed ID: 20593469
Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors.
Cancer research Aug, 2010 | Pubmed ID: 20610628
Quantifying the sensitivities of EGF receptor (EGFR) tyrosine kinase inhibitors in drug resistant non-small cell lung cancer (NSCLC) cells using hydrogel-based peptide array.
Biosensors & bioelectronics Oct, 2010 | Pubmed ID: 20729058
A magnetic bead-based protein kinase assay with dual detection techniques.
Analytical biochemistry Jan, 2011 | Pubmed ID: 20807497
Epigenetic modifications in double-strand break DNA damage signaling and repair.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2010 | Pubmed ID: 20823147
Photocleavable peptide-conjugated magnetic beads for protein kinase assays by MALDI-TOF MS.
Bioconjugate chemistry Oct, 2010 | Pubmed ID: 20860375
A pairwise chemical genetic screen identifies new inhibitors of glucose transport.
Chemistry & biology Feb, 2011 | Pubmed ID: 21338919
Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation.
Molecular cancer therapeutics Jul, 2011 | Pubmed ID: 21571912
Annotator: postprocessing software for generating function-based signatures from quantitative mass spectrometry.
Journal of proteome research Mar, 2012 | Pubmed ID: 22224429
Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2012 | Pubmed ID: 22334019
Properties of resistant cells generated from lung cancer cell lines treated with EGFR inhibitors.
BMC cancer Mar, 2012 | Pubmed ID: 22433462
Photocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MS.
Molecular bioSystems Sep, 2012 | Pubmed ID: 22772337
Activity assay of epidermal growth factor receptor tyrosine kinase inhibitors in triple-negative breast cancer cells using peptide-conjugated magnetic beads.
Assay and drug development technologies Feb, 2013 | Pubmed ID: 22994968
CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression.
Cell Dec, 2012 | Pubmed ID: 23217712
The yin and yang of cyclin control by nutrients.
Cell cycle (Georgetown, Tex.) Mar, 2013 | Pubmed ID: 23470456
Kinase activation in circulating cells: opportunities for biomarkers for diagnosis and therapeutic monitoring.
Expert opinion on medical diagnostics Jan, 2008 | Pubmed ID: 23485115
DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast.
DNA repair Sep, 2013 | Pubmed ID: 23835406
DNA-directed assembly of antibody-fluorophore conjugates for quantitative multiparametric flow cytometry.
Chembiochem : a European journal of chemical biology Jan, 2014 | Pubmed ID: 24375983
Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase.
Journal of proteomics Jan, 2015 | Pubmed ID: 25452130
Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations.
Human molecular genetics Aug, 2015 | Pubmed ID: 25948554
Ionizing radiation-induced foci persistence screen to discover enhancers of accelerated senescence.
International journal of high throughput screening Mar, 2011 | Pubmed ID: 26097382
The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage.
Data in brief Mar, 2015 | Pubmed ID: 26217697
c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells.
Cell reports Aug, 2015 | Pubmed ID: 26235616
Linking Cancer Metabolism to DNA Repair and Accelerated Senescence.
Molecular cancer research : MCR Feb, 2016 | Pubmed ID: 26538285
Acetylation of an NB-LRR Plant Immune-Effector Complex Suppresses Immunity.
Cell reports Nov, 2015 | Pubmed ID: 26586425
The dynamic interactome of human Aha1 upon Y223 phosphorylation.
Data in brief Dec, 2015 | Pubmed ID: 26693507
Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors.
Cell reports Feb, 2016 | Pubmed ID: 26804907
Nanoparticle formulations of cisplatin for cancer therapy.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 09, 2016 | Pubmed ID: 26848041
Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers.
Oncotarget Jun, 2016 | Pubmed ID: 27129153
Image-Guided Radiotherapy Targets Macromolecules through Altering the Tumor Microenvironment.
Molecular pharmaceutics Oct, 2016 | Pubmed ID: 27560921
Lipid-derived reactive aldehydes link oxidative stress to cell senescence.
Cell death & disease 09, 2016 | Pubmed ID: 27607581
Chemical inhibitors of Candida albicans hyphal morphogenesis target endocytosis.
Scientific reports 07, 2017 | Pubmed ID: 28720834
Radiation-enhanced delivery of systemically administered amphiphilic-CpG oligodeoxynucleotide.
Journal of controlled release : official journal of the Controlled Release Society Nov, 2017 | Pubmed ID: 28987882
HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation.
Molecular cancer therapeutics 02, 2018 | Pubmed ID: 29030460
Simple strategies to enhance discovery of acetylation post-translational modifications by quadrupole-orbitrap LC-MS/MS.
Biochimica et biophysica acta. Proteins and proteomics Feb, 2018 | Pubmed ID: 29050961
A signature of enhanced lipid metabolism, lipid peroxidation and aldehyde stress in therapy-induced senescence.
Cell death discovery , 2017 | Pubmed ID: 29090099
Multiplex three-dimensional optical mapping of tumor immune microenvironment.
Scientific reports 12, 2017 | Pubmed ID: 29208908
Radiation-enhanced delivery of plasmid DNA to tumors utilizing a novel PEI polyplex.
Cancer gene therapy 08, 2018 | Pubmed ID: 29255216
Three-Dimensional Analysis of the Human Pancreas.
Endocrinology 03, 2018 | Pubmed ID: 29390052
The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration.
Scientific reports 08, 2018 | Pubmed ID: 30087414
Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection.
Proceedings of the National Academy of Sciences of the United States of America 10, 2018 | Pubmed ID: 30224481
Multiplex Three-Dimensional Mapping of Macromolecular Drug Distribution in the Tumor Microenvironment.
Molecular cancer therapeutics 01, 2019 | Pubmed ID: 30322947
Nondestructive, multiplex three-dimensional mapping of immune infiltrates in core needle biopsy.
Laboratory investigation; a journal of technical methods and pathology 09, 2019 | Pubmed ID: 30401959
Quinic Acid-Conjugated Nanoparticles Enhance Drug Delivery to Solid Tumors via Interactions with Endothelial Selectins.
Small (Weinheim an der Bergstrasse, Germany) 12, 2018 | Pubmed ID: 30411856
STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability.
Cancer research 04, 2019 | Pubmed ID: 30482772
The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair.
Nucleic acids research 04, 2019 | Pubmed ID: 30812030
O-GlcNAcylation Enhances Double-Strand Break Repair, Promotes Cancer Cell Proliferation, and Prevents Therapy-Induced Senescence in Irradiated Tumors.
Molecular cancer research : MCR 06, 2019 | Pubmed ID: 30885991
Repurposing Drugs for Cancer Radiotherapy: Early Successes and Emerging Opportunities.
Cancer journal (Sudbury, Mass.) Mar/Apr, 2019 | Pubmed ID: 30896532
Targeted antibody and cytokine cancer immunotherapies through collagen affinity.
Science translational medicine 04, 2019 | Pubmed ID: 30971453
A cmap-enabled gene expression signature-matching approach identifies small-molecule inducers of accelerated cell senescence.
BMC genomics Apr, 2019 | Pubmed ID: 30987592
Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex.
Experimental & molecular medicine 04, 2019 | Pubmed ID: 30992425
Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence.
Journal of cell science 07, 2019 | Pubmed ID: 31189537
Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer.
Molecular oncology 09, 2019 | Pubmed ID: 31225926
Immune profiles in primary squamous cell carcinoma of the head and neck.
Oral oncology 09, 2019 | Pubmed ID: 31422218
The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair.
Nucleic acids research 11, 2019 | Pubmed ID: 31511892
Genetic analysis of Hsp70 phosphorylation sites reveals a role in Candida albicans cell and colony morphogenesis.
Biochimica et biophysica acta. Proteins and proteomics 03, 2020 | Pubmed ID: 31964485
Targeted Covalent Inhibition of Telomerase.
ACS chemical biology 03, 2020 | Pubmed ID: 32017522
Small-molecule drug repurposing to target DNA damage repair and response pathways.
Seminars in cancer biology 01, 2021 | Pubmed ID: 32113999
A toolkit for bioimaging using near-infrared AgInS/ZnS quantum dots.
Journal of materials chemistry. B Nov, 2015 | Pubmed ID: 32262876
Subcellular localization of the J-protein Sis1 regulates the heat shock response.
The Journal of cell biology 01, 2021 | Pubmed ID: 33326013
Lipid-derived electrophiles mediate the effects of chemotherapeutic topoisomerase I poisons.
Cell chemical biology 06, 2021 | Pubmed ID: 33352117
Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy.
Journal of the National Cancer Institute 10, 2021 | Pubmed ID: 33792717
Nuclear Sphingosine-1-phosphate Lyase Generated ∆2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells.
Cell biochemistry and biophysics Sep, 2021 | Pubmed ID: 34085165
Multiplexed Tissue Tomography.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 34331280
UltraPlex Hapten-Based Multiplexed Fluorescent Immunohistochemistry.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 34331291
Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms.
Blood 09, 2021 | Pubmed ID: 34473231
Pseudomonas syringae effector HopZ3 suppresses the bacterial AvrPto1-tomato PTO immune complex via acetylation.
PLoS pathogens 11, 2021 | Pubmed ID: 34724007
Polyphosphate degradation by Nudt3-Zn mediates oxidative stress response.
Cell reports 11, 2021 | Pubmed ID: 34788624
Genomic studies controvert the existence of the CUX1 p75 isoform.
Scientific reports 01, 2022 | Pubmed ID: 34997000
TdT-dUTP DSB End Labeling (TUDEL), for Specific, Direct In Situ Labeling of DNA Double Strand Breaks.
Methods in molecular biology (Clifton, N.J.) , 2022 | Pubmed ID: 35094335
Loss of MEN1 function impairs DNA repair capability of pancreatic neuroendocrine tumors.
Endocrine-related cancer 03, 2022 | Pubmed ID: 35171113
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