Kam W. Leong

Autologous fixed tumor vaccine: a formulation with cytokine-microparticles for protective immunity against recurrence of human hepatocellular carcinoma.

Polyphosphoester microspheres for sustained release of biologically active nerve growth factor.

Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection.

New polyphosphoramidate with a spermidine side chain as a gene carrier.

Adhesion contact dynamics of HepG2 cells on galactose-immobilized substrates.

Preparation and characterization of polypseudorotaxanes based on block-selected inclusion complexation between poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) triblock copolymers and alpha-cyclodextrin.

Microcapsules with improved mechanical stability for hepatocyte culture.

Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits.

Polyphosphoesters in drug and gene delivery.

Injectable drug-delivery systems based on supramolecular hydrogels formed by poly(ethylene oxide)s and alpha-cyclodextrin.

Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice.

In vivo US monitoring of catheter-based vascular delivery of gene microspheres in pigs: feasibility.

Multifunctional nanorods for gene delivery.

Poly(D,L-lactide-co-ethyl ethylene phosphate)s as new drug carriers.

Use of ultrathin shell microcapsules of hepatocytes in bioartificial liver-assist device.

Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters.

Thermally responsive polymeric micellar nanoparticles self-assembled from cholesteryl end-capped random poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide): synthesis, temperature-sensitivity, and morphologies.

Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance.

High density of immobilized galactose ligand enhances hepatocyte attachment and function.

Peripheral nerve regeneration by microbraided poly(L-lactide-co-glycolide) biodegradable polymer fibers.

A nonlinear hyperelastic mixture theory model for anisotropy, transport, and swelling of annulus fibrosus.

Water-soluble and nonionic polyphosphoester: synthesis, degradation, biocompatibility and enhancement of gene expression in mouse muscle.

Phase II randomized trial of autologous formalin-fixed tumor vaccine for postsurgical recurrence of hepatocellular carcinoma.

Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation.

Bioadhesive characterization of poly(methylidene malonate 2.12) microparticle on model extracellular matrix.

The effect of the degree of chitosan deacetylation on the efficiency of gene transfection.

In vitro release of vascular endothelial growth factor from gadolinium-doped biodegradable microspheres.

Poly(phosphoester) ionomers as tissue-engineering scaffolds.

Evaluation of collagen and methylated collagen as gene carriers.

Biodegradable polyphosphoester micelles for gene delivery.

Adhesion contact dynamics of primary hepatocytes on poly(ethylene terephthalate) surface.

Polyelectrolyte complex films derived from polyethyleneoxide-maleic acid copolymer and chitosan: preparation and characterization.

Encapsulation of biologics in self-assembled fibers as biostructural units for tissue engineering.

Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold.

Coculture of mesenchymal stem cells and respiratory epithelial cells to engineer a human composite respiratory mucosa.

Ternary complexes comprising polyphosphoramidate gene carriers with different types of charge groups improve transfection efficiency.

In vitro gene delivery using polyamidoamine dendrimers with a trimesyl core.

Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression.

Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes.

MR imaging of biodegradable polymeric microparticles: a potential method of monitoring local drug delivery.

Biodegradable poly(terephthalate-co-phosphate)s: synthesis, characterization and drug-release properties.

Nanopattern-induced changes in morphology and motility of smooth muscle cells.

pH responsive adhesion of phospholipid vesicle on poly(acrylic acid) cushion grafted to poly(ethylene terephthalate) surface.

Controlled release from fibers of polyelectrolyte complexes.

Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA.

Sustained release of proteins from electrospun biodegradable fibers.

Engineering microenvironment for expansion of sensitive anchorage-dependent mammalian cells.

Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells.

Biodegradable and photocrosslinkable polyphosphoester hydrogel.

Targeted tumor cell death induced by autologous tumor-specific T lymphocyte recognition of wild-type p53-derived peptides.

Micellization phenomena of biodegradable amphiphilic triblock copolymers consisting of poly(beta-hydroxyalkanoic acid) and poly(ethylene oxide).

Design of polyphosphoester-DNA nanoparticles for non-viral gene delivery.

Design of Polyphosphoester-DNA Nanoparticles for Non-Viral Gene Delivery.

Proliferation and differentiation of human embryonic germ cell derivatives in bioactive polymeric fibrous scaffold.

Evaluation of hyperbranched poly(amino ester)s of amine constitutions similar to polyethylenimine for DNA delivery.

Controlled release of heparin from poly(epsilon-caprolactone) electrospun fibers.

Surface-immobilization of adhesion peptides on substrate for ex vivo expansion of cryopreserved umbilical cord blood CD34+ cells.

Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions.

Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture.

PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo.

Nonviral gene delivery from nonwoven fibrous scaffolds fabricated by interfacial complexation of polyelectrolytes.

Dynamic and static light scattering studies on self-aggregation behavior of biodegradable amphiphilic poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]-poly(ethylene oxide) triblock copolymers in aqueous solution.

Self-assembled supramolecular hydrogels formed by biodegradable PEO-PHB-PEO triblock copolymers and alpha-cyclodextrin for controlled drug delivery.

Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture.

Radio-responsive gene therapy for malignant glioma cells without the radiosensitive promoter: Caspase-3 gene therapy combined with radiation.

Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance.

Enhanced extracellular matrix production and differentiation of human embryonic germ cell derivatives in biodegradable poly(epsilon-caprolactone-co-ethyl ethylene phosphate) scaffold.

Enhancing efficacy of HIV gag DNA vaccine by local delivery of GM-CSF in murine and macaque models.

Expansion of engrafting human hematopoietic stem/progenitor cells in three-dimensional scaffolds with surface-immobilized fibronectin.

Natural polymers for gene delivery and tissue engineering.

Hyperbranched poly(amino ester)s with different terminal amine groups for DNA delivery.

Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells.

Interaction of human mesenchymal stem cells with disc cells: changes in extracellular matrix biosynthesis.

Proliferation and differentiation of human mesenchymal stem cell encapsulated in polyelectrolyte complexation fibrous scaffold.

In vivo evaluation of plasmid DNA encoding OP-1 protein for spine fusion.

Co-culture of umbilical cord blood CD34+ cells with human mesenchymal stem cells.

Small intestinal submucosa as a potential bioscaffold for intervertebral disc regeneration.

Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET.

Dynamics of smooth muscle cell deadhesion from thermosensitive hydroxybutyl chitosan.

Biomaterials approach to expand and direct differentiation of stem cells.

Significance of synthetic nanostructures in dictating cellular response.

Effects of MIP-1 alpha, MIP-3 alpha, and MIP-3 beta on the induction of HIV Gag-specific immune response with DNA vaccines.

Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery.

In vitro chondrogenesis of mesenchymal stem cells in recombinant silk-elastinlike hydrogels.

Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage.

Tissue-engineered bone formation with gene transfer and mesenchymal stem cells in a minimally invasive technique.

Tissue compatibility of interfacial polyelectrolyte complexation fibrous scaffold: evaluation of blood compatibility and biocompatibility.

Hepatic differentiation potential of commercially available human mesenchymal stem cells.

A dual-functional fibrous scaffold enhances P450 activity of cultured primary rat hepatocytes.

Functional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cells.

Quantum-dots-FRET nanosensors for detecting unamplified nucleic acids by single molecule detection.

Chitosan nanoparticles for oral drug and gene delivery.

The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation.

In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF).

Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET.

Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry.

Poly(ethylene imine)-g-chitosan using EX-810 as a spacer for nonviral gene delivery vectors.

Radiation-inducible caspase-8 gene therapy for malignant brain tumors.

Myogenic Induction of Aligned Mesenchymal Stem Cell Sheets by Culture on Thermally Responsive Electrospun Nanofibers.

Aligned Protein-Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform.

Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles.

Viscoelastic behaviour of human mesenchymal stem cells.

Engineering strategies to enhance nanoparticle-mediated oral delivery.

Mechanical properties of single electrospun drug-encapsulated nanofibres.

The convergence of quantum-dot-mediated fluorescence resonance energy transfer and microfluidics for monitoring DNA polyplex self-assembly in real time.

Sustained viral gene delivery through core-shell fibers.

Electrohydrodynamics: A facile technique to fabricate drug delivery systems.

Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery.

Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers.

Development of universal antidotes to control aptamer activity.

Mast cell-derived particles deliver peripheral signals to remote lymph nodes.

Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells.

Transport of chitosan-DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes.

Characterization of topographical effects on macrophage behavior in a foreign body response model.

Microscale oral delivery devices incorporating nanoparticles.

Simultaneous Non-invasive Analysis of DNA Condensation and Stability by Two-step QD-FRET.

Low oxygen tension and synthetic nanogratings improve the uniformity and stemness of human mesenchymal stem cell layer.

Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency.

Electrosprayed core-shell microspheres for protein delivery.

Polymer hydrogels: Chaperoning vaccines.

Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts.

Quantum dot-based theranostics.

Nanoscale surfacing for regenerative medicine.

Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site.

Efficacy of engineered FVIII-producing skeletal muscle enhanced by growth factor-releasing co-axial electrospun fibers.

Transient depletion of kupffer cells leads to enhanced transgene expression in rat liver following retrograde intrabiliary infusion of plasmid DNA and DNA nanoparticles.

Simultaneous delivery of siRNA and paclitaxel via a "two-in-one" micelleplex promotes synergistic tumor suppression.

Deformation of stem cell nuclei by nanotopographical cues.

High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts.

Emerging links between surface nanotechnology and endocytosis: impact on nonviral gene delivery.

Engineering of a microfluidic cell culture platform embedded with nanoscale features.

Tuning physical properties of nanocomplexes through microfluidics-assisted confinement.

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics.

Dynamic topographical control of mesenchymal stem cells by culture on responsive poly(ε-caprolactone) surfaces.

Stem cell differentiation indicated by noninvasive photonic characterization and fractal analysis of subcellular architecture.

Uptake and intracellular fate of multifunctional nanoparticles: a comparison between lipoplexes and polyplexes via quantum dot mediated Förster resonance energy transfer.

Three-dimensional culture of rabbit nucleus pulposus cells in collagen microspheres.

Nucleic acid-binding polymers as anti-inflammatory agents.

Mechanical behavior of human embryonic stem cell pellet under unconfined compression.

Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate.

Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function.

Detection of single enzymatic events in rare or single cells using microfluidics.

Nucleic acid-binding polymers as anti-inflammatory agents: reducing the danger of nuclear attack.

Microfluidics-mediated isothermal detection of enzyme activity at the single molecule level.

Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes.

Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models.

Anti-infective biomaterials with surface-decorated tachyplesin I.

Walking the line: The fate of nanomaterials at biological barriers.

Editorial.

A CRISPR/Cas9-based system for reprogramming cell lineage specification.

Mitigation of hypertrophic scar contraction via an elastomeric biodegradable scaffold.

Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells.

Aptamer nanomedicine for cancer therapeutics: barriers and potential for translation.

Engineering mesenchymal stem cells for regenerative medicine and drug delivery.

NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection.

Dynamic control and quantification of bacterial population dynamics in droplets.

MicroRNA delivery for regenerative medicine.

3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.

3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.

Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels.

Transdifferentiation of human endothelial progenitors into smooth muscle cells.

Coupling spatial segregation with synthetic circuits to control bacterial survival.

Nanografted Substrata and Triculture of Human Pericytes, Fibroblasts, and Endothelial Cells for Studying the Effects on Angiogenesis.

Efficient One-Step Production of Microencapsulated Hepatocyte Spheroids with Enhanced Functions.

Poly(ethylene glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells.

Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies?

Nanoparticle-mediated inhibition of survivin to overcome drug resistance in cancer therapy.

Signal-on Protein Detection via Dye Translocation between Aptamer and Quantum Dot.

Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy.

Polycationic Nanofibers for Nucleic Acid Scavenging.

Cell-laden microfluidic microgels for tissue regeneration.

Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis.

Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage.

A versatile platform for surface modification of microfluidic droplets.

High-throughput screening of microchip-synthesized genes in programmable double-emulsion droplets.

Progress in Nanotheranostics Based on Mesoporous Silica Nanomaterial Platforms.

Diverse Applications of Nanomedicine.

Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin.

pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities.

CRISPR/Cas9-Based Genome Editing for Disease Modeling and Therapy: Challenges and Opportunities for Nonviral Delivery.

Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy.

Functional Recovery of Contused Spinal Cord in Rat with the Injection of Optimal-Dosed Cerium Oxide Nanoparticles.

Biophysical Regulation of Cell Behavior-Cross Talk between Substrate Stiffness and Nanotopography.

Application of induced pluripotent stem cells to model smooth muscle cell function in vascular diseases.

Bioreactor model of neuromuscular junction with electrical stimulation for pharmacological potency testing.

Atom Transfer Radical Polymerization of Multishelled Cationic Corona for the Systemic Delivery of siRNA.

Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide.

Human mesenchymal stem cell basal membrane bending on gratings is dependent on both grating width and curvature.

Potency of a Scalable Nanoparticulate Subunit Vaccine.

Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery.

Sustained delivery of siRNA/mesoporous silica nanoparticle complexes from nanofiber scaffolds for long-term gene silencing.

Real-time observation of leukocyte-endothelium interactions in tissue-engineered blood vessel.

Folding artificial mucosa with cell-laden hydrogels guided by mechanics models.

Uniform Core-Shell Nanoparticles with Thiolated Hyaluronic Acid Coating to Enhance Oral Delivery of Insulin.

Scarless Wound Closure by a Mussel-Inspired Poly(amidoamine) Tissue Adhesive with Tunable Degradability.

HPV Oncogene Manipulation Using Nonvirally Delivered CRISPR/Cas9 or Argonaute.

Morphology, Migration, and Transcriptome Analysis of Schwann Cell Culture on Butterfly Wings with Different Surface Architectures.

Oral Nonviral Gene Delivery for Chronic Protein Replacement Therapy.

Size-controlled lipid nanoparticle production using turbulent mixing to enhance oral DNA delivery.

Cationic nanoparticle as an inhibitor of cell-free DNA-induced inflammation.

Microfluidic Hydrodynamic Focusing for Synthesis of Nanomaterials.

Scalable Production of Therapeutic Protein Nanoparticles Using Flash Nanoprecipitation.

Hydrogen-Bonded Tannic Acid-Based Anticancer Nanoparticle for Enhancement of Oral Chemotherapy.

Scalable Manufacturing of Enteric Encapsulation Systems for Site-Specific Oral Insulin Delivery.

Advanced drug delivery systems and artificial skin grafts for skin wound healing.

Tuned Cationic Dendronized Polymer: Molecular Scavenger for Rheumatoid Arthritis Treatment.

Engineered Mesenchymal Stem Cell/Nanomedicine Spheroid as an Active Drug Delivery Platform for Combinational Glioblastoma Therapy.

Sustained release of exendin-4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes.

Scaffold-mediated non-viral delivery platform for CRISPR/Cas9-based genome editing.

Spatial metagenomic characterization of microbial biogeography in the gut.

Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1.

Engineering Cell Membrane-Based Nanotherapeutics to Target Inflammation.

Biomaterial-assisted scalable cell production for cell therapy.

A polyphenol-metal nanoparticle platform for tunable release of liraglutide to improve blood glycemic control and reduce cardiovascular complications in a mouse model of type II diabetes.

CRISPR/Cas9-mediated mutagenesis to validate the synergy between PARP1 inhibition and chemotherapy in -mutated breast cancer cells.

Flash Fabrication of Orally Targeted Nanocomplexes for Improved Transport of Salmon Calcitonin across the Intestine.

Revascularization and limb salvage following critical limb ischemia by nanoceria-induced Ref-1/APE1-dependent angiogenesis.

Dual-Color Plasmonic Nanosensor for Radiation Dosimetry.

Identification of Specific Joint-Inflammatogenic Cell-Free DNA Molecules From Synovial Fluids of Patients With Rheumatoid Arthritis.

Treatment of severe sepsis with nanoparticulate cell-free DNA scavengers.

Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain.

Correction: A highly selective dual-therapeutic nanosystem for simultaneous anticancer and antiangiogenesis therapy.

Advances in microphysiological blood-brain barrier (BBB) models towards drug delivery.

Protein-reactive nanofibrils decorated with cartilage-derived decellularized extracellular matrix for osteochondral defects.

CRISPR Technology for Breast Cancer: Diagnostics, Modeling, and Therapy.

Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects.

Prevention of excessive scar formation using nanofibrous meshes made of biodegradable elastomer poly(3-hydroxybutyrate--3-hydroxyvalerate).

High-Throughput Tumor-on-a-Chip Platform to Study Tumor-Stroma Interactions and Drug Pharmacokinetics.

An implantable blood clot-based immune niche for enhanced cancer vaccination.

A Versatile Nonviral Delivery System for Multiplex Gene-Editing in the Liver.

A materials-science perspective on tackling COVID-19.

Nanoparticle-Enabled Dual Modulation of Phagocytic Signals to Improve Macrophage-Mediated Cancer Immunotherapy.

Biomimetic Diselenide-Bridged Mesoporous Organosilica Nanoparticles as an X-ray-Responsive Biodegradable Carrier for Chemo-Immunotherapy.

Microfluidic Isolation and Enrichment of Nanoparticles.

Engineering liver microtissues for disease modeling and regenerative medicine.

Determination of Cellular Uptake and Endocytic Pathways.

A Cationic Metal-Organic Framework to Scavenge Cell-Free DNA for Severe Sepsis Management.

Modeling SARS-CoV-2 infection in individuals with opioid use disorder with brain organoids.

The NIH Somatic Cell Genome Editing program.

Emulating Early Atherosclerosis in a Vascular Microphysiological System Using Branched Tissue-Engineered Blood Vessels.

Promoting reactive oxygen species generation: a key strategy in nanosensitizer-mediated radiotherapy.

Dose-Dependent Carbon-Dot-Induced ROS Promote Uveal Melanoma Cell Tumorigenicity via Activation of mTOR Signaling and Glutamine Metabolism.

Inhibition of DNA replication initiation by silver nanoclusters.

Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration.

Biofunctional Janus particles promote phagocytosis of tumor cells by macrophages.

Scaffold-mediated CRISPR-Cas9 delivery system for acute myeloid leukemia therapy.

Drug delivery carriers with therapeutic functions.

A Versatile and Robust Platform for the Scalable Manufacture of Biomimetic Nanovaccines.

Flash Technology-Based Self-Assembly in Nanoformulation: From Fabrication to Biomedical Applications.

Light: A Magical Tool for Controlled Drug Delivery.

Systemic antiviral immunization by virus-mimicking nanoparticles-decorated erythrocytes.

Investigation of Neurodevelopmental Deficits of 22 q11.2 Deletion Syndrome with a Patient-iPSC-Derived Blood-Brain Barrier Model.

Engineered biomaterials for cancer immunotherapy.

A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury.

Nanotechnology for Pain Management: Current and Future Therapeutic Interventions.

A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease.

Biomaterialomics: Data science-driven pathways to develop fourth-generation biomaterials.

Design of therapeutic biomaterials to control inflammation.

A programmable encapsulation system improves delivery of therapeutic bacteria in mice.

Scalable biomimetic SARS-CoV‑2 nanovaccines with robust protective immune responses.

DAMPs/PAMPs induce monocytic TLR activation and tolerance in COVID-19 patients; nucleic acid binding scavengers can counteract such TLR agonists.

Blood-brain barrier-penetrating single CRISPR-Cas9 nanocapsules for effective and safe glioblastoma gene therapy.

Correction: Biofunctional Janus particles promote phagocytosis of tumor cells by macrophages.

Material Engineering in Gut Microbiome and Human Health.

Spatial profiling of chromatin accessibility in mouse and human tissues.

Challenges and opportunities for the next generation of cardiovascular tissue engineering.

Chemically-induced osteogenic cells for bone tissue engineering and disease modeling.

Dendritic cell-mimicking scaffolds for ex vivo T cell expansion.

Corrigendum to "Chemically-induced osteogenic cells for bone tissue engineering and disease modeling" [Biomaterials 289 (2022) 121792].

Nanoparticulate cell-free DNA scavenger for treating inflammatory bone loss in periodontitis.

Therapeutic Nanocarriers Inhibit Chemotherapy-Induced Breast Cancer Metastasis.

Probiotic-Inspired Nanomedicine Restores Intestinal Homeostasis in Colitis by Regulating Redox Balance, Immune Responses, and the Gut Microbiome.

Targeting Proinflammatory Molecules Using Multifunctional MnO Nanoparticles to Inhibit Breast Cancer Recurrence and Metastasis.

A miRNA-based gene therapy nanodrug synergistically enhances pro-inflammatory antitumor immunity against melanoma.

Delivery of Induced Neural Stem Cells Through Mechano-Tuned Silk-Collagen Hydrogels for the Recovery of Contused Spinal Cord in Rats.

Polycationic PAMAM ameliorates obesity-associated chronic inflammation and focal adiposity.

Selective targeting of visceral adiposity by polycation nanomedicine.

A mineralizing pool of Gli1-expressing progenitors builds the tendon enthesis and demonstrates therapeutic potential.

Phenylboronic Acid-Functionalized Polyplexes Tailored to Oral CRISPR Delivery.

Inhibition of Abl Kinase by Imatinib Can Rescue the Compromised Barrier Function of 22q11.2DS Patient-iPSC-Derived Blood-Brain Barriers.

Spatial epigenome-transcriptome co-profiling of mammalian tissues.

The Year 2022 in biomaterials research: A perspective from the editors of six leading journals.

Circulating Cell-Free DNAs as a Biomarker and Therapeutic Target for Acetaminophen-Induced Liver Injury.

Scalable projected Light Sheet Microscopy for high-resolution imaging of living and cleared samples.

MDM2-Targeting Reassembly Peptide (TRAP) Nanoparticles for p53-Based Cancer Therapy.

Thiol-Disulfide Exchange Coordinates the Release of Nitric Oxide and Dexamethasone for Synergistic Regulation of Intestinal Microenvironment in Colitis.

Plant cell-based drug delivery enhances affordability of biologics.

Focused ultrasound-mediated brain genome editing.

Modeling and countering the effects of cosmic radiation using bioengineered human tissues.

Delivery of biologics: Topical administration.

PCSK9 activation promotes early atherosclerosis in a vascular microphysiological system.

Cationic mesoporous silica nanoparticles alleviate osteoarthritis by targeting multiple inflammatory mediators.

Multifunctional Cationic Hyperbranched Polyaminoglycosides that Target Multiple Mediators for Severe Abdominal Trauma Management.

Enabling continuous immune cell recirculation on a microfluidic array to study immunotherapeutic interactions in a recapitulated tumour microenvironment.

Isotropic multi-scale neuronal reconstruction from high-ratio expansion microscopy with contrastive unsupervised deep generative models.

Comparative Analysis of Nucleic Acid-Binding Polymers as Potential Anti-Inflammatory Nanocarriers.

Inhaled immunoantimicrobials for the treatment of chronic obstructive pulmonary disease.

Human vascular organoids with a mosaic mutation recapitulate Proteus syndrome.

Tackling Severe Neutrophilic Inflammation in Airway Disorders with Functionalized Nanosheets.

Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor-immune hubs.

Chronic Opioid Treatment Arrests Neurodevelopment and Alters Synaptic Activity in Human Midbrain Organoids.

Optimization of lipid nanoparticles for gene editing of the liver via intraduodenal delivery.

An Engineered Nanoplatform with Tropism Toward Irradiated Glioblastoma Augments Its Radioimmunotherapy Efficacy.

Multiscale engineering of brain organoids for disease modeling.

Degradation-resistant implanted biomaterials establish an immunosuppressive microenvironment that induces T cell exhaustion by recruiting myeloid cells.

Bacterial therapies at the interface of synthetic biology and nanomedicine.

Modeling the Effects of Protracted Cosmic Radiation in a Human Organ-on-Chip Platform.

Nanodiamonds in biomedical research: Therapeutic applications and beyond.

Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples.

PAR on oral cancer cells and nociceptors contributes to oral cancer pain that can be relieved by nanoparticle-encapsulated AZ3451.

Discovery of nanobodies: a comprehensive review of their applications and potential over the past five years.

Targeted protein degradation via cellular trafficking of nanoparticles.

Iron-Tannin Coating Reduces Clearance and Increases Tumor Colonization of Systemically Delivered Bacteria.

Bimetallic peroxide-based nanotherapeutics for immunometabolic intervention and induction of immunogenic cell death to augment cancer immunotherapy.

Nanomaterial-Mediated Reprogramming of Macrophages to Inhibit Refractory Muscle Fibrosis.

Magnetic soft microrobots for erectile dysfunction therapy.

Sound innovations for biofabrication and tissue engineering.