Biology Department and Heart Institute
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The myosin converter domain modulates muscle performance.
Nature cell biology Apr, 2002 | Pubmed ID: 11901423
The converter domain modulates kinetic properties of Drosophila myosin.
American journal of physiology. Cell physiology Apr, 2003 | Pubmed ID: 12477668
Variable N-terminal regions of muscle myosin heavy chain modulate ATPase rate and actin sliding velocity.
The Journal of biological chemistry May, 2003 | Pubmed ID: 12606545
Drosophila paramyosin is important for myoblast fusion and essential for myofibril formation.
The Journal of cell biology Mar, 2003 | Pubmed ID: 12642615
UCS proteins: managing the myosin motor.
Current biology : CB Jul, 2003 | Pubmed ID: 12842031
Kinetic analysis of Drosophila muscle myosin isoforms suggests a novel mode of mechanochemical coupling.
The Journal of biological chemistry Dec, 2003 | Pubmed ID: 14506231
Alternative N-terminal regions of Drosophila myosin heavy chain tune muscle kinetics for optimal power output.
Biophysical journal Sep, 2004 | Pubmed ID: 15345559
Passive stiffness of Drosophila IFM myofibrils: a novel, high accuracy measurement method.
Journal of muscle research and cell motility , 2004 | Pubmed ID: 15548865
Drosophila paramyosin is important for myoblast fusion and essential for myofibril formation.
The Journal of cell biology Nov, 2004 | Pubmed ID: 15557126
Paramyosin phosphorylation site disruption affects indirect flight muscle stiffness and power generation in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2005 | Pubmed ID: 16020538
An alternative domain near the nucleotide-binding site of Drosophila muscle myosin affects ATPase kinetics.
Journal of molecular biology Oct, 2005 | Pubmed ID: 16154586
An alternative domain near the ATP binding pocket of Drosophila myosin affects muscle fiber kinetics.
Biophysical journal Apr, 2006 | Pubmed ID: 16399836
alphaB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress.
Journal of molecular biology May, 2006 | Pubmed ID: 16546210
Passive stiffness in Drosophila indirect flight muscle reduced by disrupting paramyosin phosphorylation, but not by embryonic myosin S2 hinge substitution.
Biophysical journal Dec, 2006 | Pubmed ID: 17012313
Transcriptional regulation of the Drosophila melanogaster muscle myosin heavy-chain gene.
Gene expression patterns : GEP Feb, 2007 | Pubmed ID: 17194628
Alternative S2 hinge regions of the myosin rod differentially affect muscle function, myofibril dimensions and myosin tail length.
Journal of molecular biology Apr, 2007 | Pubmed ID: 17316684
A variable domain near the ATP-binding site in Drosophila muscle myosin is part of the communication pathway between the nucleotide and actin-binding sites.
Journal of molecular biology May, 2007 | Pubmed ID: 17379245
Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles.
Molecular biology of the cell Feb, 2008 | Pubmed ID: 18045988
Alternative relay domains of Drosophila melanogaster myosin differentially affect ATPase activity, in vitro motility, myofibril structure and muscle function.
Journal of molecular biology Jun, 2008 | Pubmed ID: 18462751
Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles.
Journal of molecular biology Sep, 2008 | Pubmed ID: 18588896
Alternative versions of the myosin relay domain differentially respond to load to influence Drosophila muscle kinetics.
Biophysical journal Dec, 2008 | Pubmed ID: 18805920
The XXXVII European muscle conference: Oxford September 2008.
Journal of muscle research and cell motility , 2008 | Pubmed ID: 19034677
Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head.
Journal of molecular biology Jun, 2009 | Pubmed ID: 19393244
Alternative S2 hinge regions of the myosin rod affect myofibrillar structure and myosin kinetics.
Biophysical journal May, 2009 | Pubmed ID: 19450484
Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight ability.
Journal of molecular biology May, 2010 | Pubmed ID: 20362584
Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase.
Biochemical and biophysical research communications May, 2010 | Pubmed ID: 20403336
Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability.
Journal of cell science Mar, 2011 | Pubmed ID: 21285246
X-ray crystal structure of the UCS domain-containing UNC-45 myosin chaperone from Drosophila melanogaster.
Structure (London, England : 1993) Mar, 2011 | Pubmed ID: 21397190
A mighty small heart: the cardiac proteome of adult Drosophila melanogaster.
PloS one , 2011 | Pubmed ID: 21541028
Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities.
The Journal of biological chemistry Aug, 2011 | Pubmed ID: 21680742
The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model.
PloS one , 2011 | Pubmed ID: 21799905
Disrupting the myosin converter-relay interface impairs Drosophila indirect flight muscle performance.
Biophysical journal Sep, 2011 | Pubmed ID: 21889448
Structural basis for myopathic defects engendered by alterations in the myosin rod.
Journal of molecular biology Dec, 2011 | Pubmed ID: 22037585
Transgenic expression and purification of myosin isoforms using the Drosophila melanogaster indirect flight muscle system.
Methods (San Diego, Calif.) Dec, 2011 | Pubmed ID: 22178692
Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction.
Journal of cellular and molecular medicine Jan, 2012 | Pubmed ID: 22225769
Alternative Relay and Converter Domains Tune Native Muscle Myosin Isoform Function in Drosophila.
Journal of molecular biology Dec, 2011 | Pubmed ID: 22226837
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