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JoVE Journal

Immunology and Infection

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The Utilization of Oropharyngeal Intratracheal PAMP Administration and Bronchoalveolar Lavage to Evaluate the Host Immune Response in Mice

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12:27 min

April 2nd, 2014

April 2nd, 2014

16,481 Views

0:05

Title

1:24

Serum and Bronchoalveolar Lavage Fluid (BALF) Collection

5:27

Histopathology Preparation

7:52

Results: Representative Immuno- and Histopathological Analyses of LPS-treated Lung Tissue

12:00

Conclusion

The host immune response to pathogen infection is a tightly regulated process. Utilizing a lipopolysaccharide lung exposure model in mice, it is possible to conduct high resolution evaluations of the complex mechanisms associated with disease pathogenesis.

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