JoVE Journal

Medicine

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Um modelo murino de irreversível e reversível obstrução ureteral unilateral

29.9K Views

14:05 min

December 20th, 2014

December 20th, 2014


0:00

Title

2:22

Surgical Preparation

3:40

Unilateral Ureteric Obstruction

4:33

Preparation for Reversible Unilateral Ureteric Obstruction

6:20

Post-operative Care

6:58

Reversible Unilateral Ureteric Obstruction

11:39

Representative Results

13:04

Conclusion

The murine model of irreversible unilateral ureteric obstruction (UUO) is presented together with the model of reversible UUO in which the ureteric obstruction is relieved by anastomosis of the severed ureter into the bladder. These models enable the study of renal inflammation and scarring as well as tissue remodeling.

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