Tomasz Huc

Intracolonic hydrogen sulfide lowers blood pressure in rats.

Renal denervation decreases blood pressure and renal tyrosine hydroxylase but does not augment the effect of hypotensive drugs.

Colonic hydrogen sulfide produces portal hypertension and systemic hypotension in rats.

Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite.

Indole and indoxyl sulfate, gut bacteria metabolites of tryptophan, change arterial blood pressure via peripheral and central mechanisms in rats.

High salt intake increases plasma trimethylamine N-oxide (TMAO) concentration and produces gut dysbiosis in rats.

Colonic indole, gut bacteria metabolite of tryptophan, increases portal blood pressure in rats.

CHRONIC, LOW-DOSE TMAO TREATMENT REDUCES DIASTOLIC DYSFUNCTION AND HEART FIBROSIS IN HYPERTENSIVE RATS.