Shuangping Shi

MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis.

Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes.

Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alphabeta receptor and STAT1.

Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88.

Dihydrolipoamide acyltransferase is critical for Mycobacterium tuberculosis pathogenesis.

mRNA stability and antibody production in CHO cells: improvement through gene optimization.

Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.