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Candida albicans Biofilm Chip (CaBChip) for High-throughput Antifungal Drug Screening

DOI :

10.3791/3845-v

July 18th, 2012

July 18th, 2012

13,540 Views

1Department of Biomedical Engineering, University of Texas at San Antonio , 2Department of Biology, University of Texas at San Antonio

We have developed a high-density microarray platform consisting of 3D nano-biofilms of C. albicans called CaBChip. The susceptibility profile of drugs tested on a CaBChip is comparable to the conventional 96-well plate model, suggesting that the fungal chip is ideally suited for true high-throughput screening of antifungal drugs.

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Candida Albicans

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