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Viral Nanoparticles for In vivo Tumor Imaging

DOI :

10.3791/4352-v

November 16th, 2012

November 16th, 2012

16,897 Views

1Department of Biomedical Engineering, Case Western Reserve University , 2Department of Biomedical Engineering, Radiology, and Materials Science and Engineering, Case Western Reserve University

Plant viral nanoparticles (VNPs) are promising platforms for applications in biomedicine. Here, we describe the procedures for plant VNP propagation, purification, characterization, and bioconjugation. Finally, we show the application of VNPs for tumor homing and imaging using a mouse xenograft model and fluorescence imaging.

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Nanoparticles

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