JoVE Logo
Faculty Resource Center

Sign In

Correlative Light Electron Microscopy CLEM for Tracking and Imaging Viral Protein Associated Structures in Cryo-immobilized Cells Video (Video) | JoVE

DOI :

10.3791/58154-v

9:18 min

September 7th, 2018

September 7th, 2018

79,012 Views

1European Molecular Biology Laboratory, 2Department of Infectious Diseases, Molecular Virology, Heidelberg University, 3Central Facility for Electron Microscopy, Ulm University, 4Heidelberg Partner Site, German Center for Infection Research

A correlative light electron microscopy (CLEM) method is applied to image virus-induced intracellular structures via electron microscopy (EM) in cells that are previously selected by light microscopy (LM). LM and EM are combined as a hybrid imaging approach to achieve an integrated view of virus-host interactions.

Tags

Correlative Light Electron Microscopy CLEM

-- Views

Related Videos

article

Three-dimensional Optical-resolution Photoacoustic Microscopy (Video) | JoVE

article

Low-Cost Cryo-Light Microscopy Stage Fabrication for Correlated Light/Electron Microscopy (Video) | JoVE

article

Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement (Video) | JoVE

article

Video-rate Scanning Confocal Microscopy and Microendoscopy (Video) | JoVE

article

Viral Nanoparticles for In vivo Tumor Imaging (Video) | JoVE

article

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions (Video) | JoVE

article

In situ Compressive Loading and Correlative Noninvasive Imaging of the Bone-periodontal Ligament-tooth Fibrous Joint (Video) | JoVE

article

Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging Video (Video) | JoVE

article

Studying the Stoichiometry of Epidermal Growth Factor Receptor in Intact Cells using Correlative Microscopy Video (Video) | JoVE

article

Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles Video (Video) | JoVE

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved