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Recording and Analysis of Circadian Rhythms in Running-wheel Activity in Rodents

DOI :

10.3791/50186-v

January 24th, 2013

January 24th, 2013

20,483 Views

1Douglas Mental Health University Institute, Department of Psychiatry, McGill University , 2Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University

Circadian rhythms in voluntary wheel-running activity in mammals are tightly coupled to the molecular oscillations of a master clock in the brain. As such, these daily rhythms in behavior can be used to study the influence of genetic, pharmacological, and environmental factors on the functioning of this circadian clock.

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