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Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

DOI :

10.3791/50476-v

July 25th, 2013

July 25th, 2013

16,839 Views

1Department of Chemical and Biological Engineering, Princeton University

We developed computational de novo protein design methods capable of tackling several important areas of protein design. To disseminate these methods we present Protein WISDOM, an online tool for protein design (http://www.proteinwisdom.org). Starting from a structural template, design of monomeric proteins for increased stability and complexes for increased binding affinity can be performed.

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Protein WISDOM

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