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Electrospinning Growth Factor Releasing Microspheres into Fibrous Scaffolds

DOI :

10.3791/51517-v

August 16th, 2014

August 16th, 2014

12,090 Views

1Biomedical Engineering, Wayne State University

This protocol combines electrospinning and microspheres to develop tissue engineered scaffolds to direct neurons. Nerve growth factor was encapsulated within PLGA microspheres and electrospun into Hyaluronic Acid (HA) fibrous scaffolds. The protein bioactivity was tested by seeding the scaffolds with primary chick Dorsal Root Ganglia and culturing for 4-6 days.

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Electrospinning

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