Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
17.1K Views
•
18:40 min
•
October 16th, 2014
DOI :
October 16th, 2014
•Nicholas M. Bernthal1, Brad N. Taylor2, Jeffrey A. Meganck2, Yu Wang3, Jonathan H. Shahbazian3, Jared A. Niska1, Kevin P. Francis2, Lloyd S. Miller3,4
1Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California, Los Angeles (UCLA), 2PerkinElmer, 3Department of Dermatology, Johns Hopkins University School of Medicine, 4Department of Medicine, Division of Infectious Diseases, Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine
Chapters in this video
0:05
Title
1:51
Mouse Surgical Procedure
3:56
2D Optical Imaging (In vivo Bioluminescent and Fluorescent Imaging)
6:35
µCT Image Acquisition
8:11
3D Optical Image Acquisition, Formation and µCT Co-registration
12:18
µCT Image Analysis
16:09
Results: Representative Bioluminescent and µCT Images
17:49
Conclusion
Related Videos
08:04
Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging
24.5K Views
10:30
Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair
10.5K Views
13:16
Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
11.4K Views
06:10
Real-Time Imaging of CCL5-Induced Migration of Periosteal Skeletal Stem Cells in Mice
2.2K Views
07:48
High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
1.2K Views
08:41
Femur Window Chamber Model for In Vivo Cell Tracking in the Murine Bone Marrow
8.1K Views
06:38
Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
10.0K Views
07:33
In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur
9.5K Views
08:03
In Vivo Mouse Model of Spinal Implant Infection
2.3K Views
06:59
Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
2.1K Views
Copyright © 2025 MyJoVE Corporation. All rights reserved