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An Isolated Working Heart System for Large Animal Models

DOI :

10.3791/51671-v

9:45 min

June 11th, 2014

June 11th, 2014

29,757 Views

1Department of Surgery, Duke University Medical Center, 2Department of Cardiothoracic Surgery, University Hospital of South Manchester

Most studies involving the Langendorff apparatus use small animal models due to the increased complexity of systems for larger mammals. We describe a Langendorff system for large animal models that allows for use across a range of species, including humans, and relatively easy data acquisition.

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Keywords Langendorff Isolated Heart Perfusion

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