September 18th, 2016
•We report a device and a new method to study cells and embryos. Single cells are precisely ordered in microcavity arrays. Their 3D confinement is a step towards 3D environments encountered in physiological conditions and allows organelle orientation. By controlling cell shape, this setup minimizes variability reported in standard assays.
Tags
Related Videos
Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement
A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
Nanomanipulation of Single RNA Molecules by Optical Tweezers
Cultivation of Mammalian Cells Using a Single-use Pneumatic Bioreactor System
A Microfluidic Platform for High-throughput Single-cell Isolation and Culture
3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening
A Protocol for Real-time 3D Single Particle Tracking
Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells
Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy
Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved