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Creating Anatomically Accurate and Reproducible Intracranial Xenografts of Human Brain Tumors

DOI :

10.3791/52017-v

September 24th, 2014

September 24th, 2014

15,266 Views

1Department of Pediatrics, University of Colorado School of Medicine

The brain is a unique site with qualities that are not well represented by in vitro or ectopic analyses. Orthotopic mouse models with reproducible location and growth characteristics can be reliably created with intracranial injections using a stereotaxic fixation instrument and a low pressure syringe pump.

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Keywords Orthotopic Tumor Models

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