JoVE Logo
Faculty Resource Center

Sign In

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

DOI :

10.3791/52018-v

8:27 min

October 29th, 2014

October 29th, 2014

10,525 Views

1School of Pharmacy, University College London, 2Mucin Biology Group, University of Gothenburg

Here, a procedure is described for the establishment of systemic infection in the neonatal rat with cultures of Escherichia coli K1. This non-invasive procedure permits colonization of the gastrointestinal tract, translocation of the pathogen to the systemic circulation, and invasion of the central nervous system at the choroid plexus.

Tags

Non invasive Model

-- Views

Related Videos

article

Non-invasive Imaging of Leukocyte Homing and Migration in vivo

article

Non-invasive Imaging of Disseminated Candidiasis in Zebrafish Larvae

article

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

article

Culturing Microglia from the Neonatal and Adult Central Nervous System

article

Complete Thymectomy in Adult Rats with Non-invasive Endotracheal Intubation

article

Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection

article

One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode

article

Detection of Enterohemorrhagic Escherichia Coli Colonization in Murine Host by Non-invasive In Vivo Bioluminescence System

article

Overexpression and Purification of Human Cis-prenyltransferase in Escherichia coli

article

A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved