Porous Silicon Microparticles for Delivery of siRNA Therapeutics
10.9K Views
•
08:31 min
•
January 15th, 2015
DOI :
January 15th, 2015
•Jianliang Shen*1,2, Xiaoyan Wu*1,3, Yeonju Lee1, Joy Wolfram1,4, Zhizhou Yang1, Zong-Wan Mao2, Mauro Ferrari1,5, Haifa Shen1,6
1Department of Nanomedicine, Houston Methodist Research Institute, 2MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 3Pediatrics Department of Union Hospital, Huazhong University of Science and Technology, 4CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, National Center for Nanoscience & Technology of China, 5Department of Medicine, Weill Cornell Medical College, 6Department of Cell and Developmental Biology, Weill Cornell Medical College
Chapters in this video
0:05
Title
0:58
PCPS Particle Preparation
3:46
PCPS Particle Characterization
4:33
Loading of siRNA into PCPS Particles and Optimization of siRNA/PCPS Particle Ratio
5:31
Release of siRNA from PCPS Particles
6:16
Results: Characterization of Porous Silicon Microparticles for siRNA Delivery
8:02
Conclusion
Related Videos
09:59
Preparation of Exosomes for siRNA Delivery to Cancer Cells
24.7K Views
09:12
Nanoparticle-mediated siRNA Gene-silencing in Adult Zebrafish Heart
8.1K Views
08:53
Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery
7.5K Views
10:33
Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
10.4K Views
08:44
Assembly and Characterization of Polyelectrolyte Complex Micelles
10.6K Views
06:02
Production of siRNA-Loaded Lipid Nanoparticles using a Microfluidic Device
8.8K Views
11:53
Predicting Gene Silencing Through the Spatiotemporal Control of siRNA Release from Photo-responsive Polymeric Nanocarriers
7.2K Views
10:12
Designing Porous Silicon Films as Carriers of Nerve Growth Factor
9.7K Views
09:09
Preparation of Neutrally-charged, pH-responsive Polymeric Nanoparticles for Cytosolic siRNA Delivery
7.4K Views
15:55
Long-term Silencing of Intersectin-1s in Mouse Lungs by Repeated Delivery of a Specific siRNA via Cationic Liposomes. Evaluation of Knockdown Effects by Electron Microscopy
10.6K Views
Copyright © 2025 MyJoVE Corporation. All rights reserved