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Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors

DOI :

10.3791/52653-v

May 10th, 2015

May 10th, 2015

13,778 Views

1Department of Biology, The Pennsylvania State University

Stereotactic injection of lentiviruses expressing cDNAs or shRNAs can modulate gene expression in specific brain areas of mice. Here, we present a protocol to combine stereotactic injections with behavioral tasks, such as the Open Field Test (OFT) and the Forced Swim Test (FST).

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Stereotactic Injection

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