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An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans

DOI :

10.3791/52681-v

April 9th, 2015

April 9th, 2015

8,399 Views

1Department of Pharmacology and Toxicology, Virginia Commonwealth University, 2VCU Alcohol Research Center, Virginia Commonwealth University

C. elegans is a useful model for studying the effects of ethanol on behavior. We present a behavioral assay that quantifies the effects of ethanol on the locomotion speed of crawling worms; both initial sensitivity and the development of acute functional tolerance to ethanol can be measured with this assay.

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