Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits

41.6K Views

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08:01 min

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March 16th, 2016

DOI :

10.3791/53308-v

March 16th, 2016

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Hye Yun Kim¹^,², Dongkeun K. Lee¹, Bo-Ryehn Chung¹^,³, Hyunjin V. Kim¹^,⁴, YoungSoo Kim¹^,⁴

¹Center for Neuro-Medicine, Korea Institute of Science and Technology, ²Research Institute, GoshenBiotech, Inc., ³Department of Chemical and Biological Engineering, Princeton University, ⁴Biological Chemistry Program, Korea University of Science and Technology

Summary

Chapters in this video

0:05

Title

1:30

Aβ Peptide and Syringe Preparation

2:54

Aβ Injection in Mouse

6:06

Results: Confirmation of Prepared Aβ Species via SDS-PAGE and Y-maze Behavioral Tests

7:07

Conclusion

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