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Protocol for the Direct Conversion of Murine Embryonic Fibroblasts into Trophoblast Stem Cells

DOI :

10.3791/54277-v

July 25th, 2016

July 25th, 2016

7,464 Views

1Department of Developmental Pathology, Institute of Pathology, University of Bonn Medical School

Here we present a protocol for the direct conversion of murine embryonic fibroblasts into fully functional and stable trophoblast stem cells by ten day over-expression of Tfap2c, Gata3, Eomes and Ets2.

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