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A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules

DOI :

10.3791/55199-v

March 10th, 2017

March 10th, 2017

10,073 Views

1Department of Microbiology, Infectiology and Immunology, Université de Montréal, 2Department of Pharmacology and Physiology, Université de Montréal, 3Molecular Biology Program, Université de Montréal

We present in the current study a novel fluorescence-based assay using lymphocytes derived from a transgenic mouse. This assay is suitable for high-throughput screening (HTS) of small molecules endowed with the capacity of either inhibiting or promoting lymphocyte activation.

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