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A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells

DOI :

10.3791/50369-v

July 3rd, 2013

July 3rd, 2013

10,899 Views

1Department of Cell Biology, UT Southwestern Medical Center

Achieving a systems level understanding of cellular processes is a goal of modern-day cell biology. We describe here strategies for multiplexing luciferase reporters of various cellular function end-points to interrogate gene function using genome-scale RNAi libraries.

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