A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder

10.5K Views

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07:51 min

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June 18th, 2018

DOI :

10.3791/55864-v

June 18th, 2018

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Andrea L. Dimet*¹^,²^,³, Irma E. Cisneros*¹^,⁴^,⁵, Robert G. Fox¹^,⁶, Sonja J. Stutz¹^,⁶, Noelle C. Anastasio¹^,⁶, Kathryn A. Cunningham¹^,⁶, Kelly T. Dineley¹^,³^,⁴

¹Center for Addiction Research, University of Texas Medical Branch, ²Institute for Translational Sciences, University of Texas Medical Branch, ³Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, ⁴Department of Neurology, University of Texas Medical Branch, ⁵Department of Pathology, University of Texas Medical Branch, ⁶Department of Pharmacology and Toxicology, University of Texas Medical Branch

Summary

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Keywords Cue Reactivity

Cocaine Use Disorder

Relapse Risk

Operant Task

Drug seeking Behavior

Pre clinical

Pharmacotherapies

Genetic Factors

Environmental Factors

Sprague Dawley Rats

Jugular Vein Catheters

Cocaine Self administration

Chapters in this video

0:04

Title

1:01

Preparing Rats for the Training

2:28

Self-Administration Training

4:59

Forced Abstinence and Cue Reactivity Testing

6:08

Results: Cue Reactivity Test Data

7:08

Conclusion

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