Surgery: Portal Vein Ligation with the Associating Liver Partition for Staged Hepatectomy (ALPPS)
5:55
Results: Growth Kinetics of Liver Post-PVL or Post-ALPPS Surgery
6:28
Conclusion
Transcript
The overall goal of this surgical intervention is to achieve rapid hypertrophy of the rat liver by ligation of the portal vein and transection of the parenchyma. This model allows for details physiological and molecular assessments of rapid liver
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Inducing rapid liver hypertrophy using Associating Liver Partition and Portal vein ligation for a Staged hepatectomy (ALPPS) has been proposed for resection of borderline resectable liver tumors. This model may elucidate mechanisms involved in rapid hypertrophy and allows testing of drugs that promote or block the acceleration of regeneration.