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The Dimethylnitrosamine Induced Liver Fibrosis Model in the Rat

DOI :

10.3791/54208-v

June 17th, 2016

June 17th, 2016

11,552 Views

1Technology Development, School of Applied Science, Temasek Polytechnic

We describe a method to produce an animal model of liver fibrosis in the rat, and assess the degree of fibrosis by histological examination of the liver. The model can be used to study the development of liver disease as well as to test the efficacy of potential anti-fibrotic agents.

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