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Chip-based Three-dimensional Cell Culture in Perfused Micro-bioreactors

DOI :

10.3791/564-v

May 21st, 2008

May 21st, 2008

11,093 Views

1Institute for Biological Interfaces, Forschungszentrum Karlsruhe

We describe a chip-based platform for the three-dimensional cultivation of cells in micro-bioreactors. One chip can house up to 10 Mio. cells that can be cultivated under precisely defined conditions with regard to fluid flow, oxygen tension etc. in a sterile, closed circulation loop.

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Chip based

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