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The Multi-organ Chip - A Microfluidic Platform for Long-term Multi-tissue Coculture

DOI :

10.3791/52526-v

10:05 min

April 28th, 2015

April 28th, 2015

27,788 Views

1Medical Biotechnology, Technische Universität Berlin, 2TissUse GmbH, 3Fraunhofer IWS

Here, we present a protocol to coculture primary cells, tissue models and punch biopsies in a microfluidic multi-organ chip for up to 28 days. Human dermal microvascular endothelial cells, liver aggregates and skin biopsies were successfully combined in a common media circulation.

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Multi organ Chip

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