Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
2.9K Views
•
07:41 min
•
March 17th, 2022
DOI :
March 17th, 2022
•David Boulate1, Myriam Amsallem1,2, Jean-Baptiste Menager1, Simon Dang Van1, Peter Dorfmuller3, Andrew Connolly4, Alban Todesco5, Benoit Decante1, Elie Fadel1, Francois Haddad2, Olaf Mercier1
1Research and Innovation Unit, RHU BioArt Lung 2020, Marie Lannelongue Hospital, 2Phenotypic and Biomarker Core Laboratory, Cardiovascular Institute, Stanford University, 3Department of pathology, Marie Lannelongue Hospital, 4Department of pathology, UCSF School of Medicine, 5Department of thoracic surgery, Hopital Nord, APHM, Aix-Marseille University
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Chapters in this video
0:04
Introduction
0:39
Catheter Placement
1:44
Echocardiography
2:19
Right Heart Catheterization and Pressure Volume Loop Acquisition
3:20
Acute Right Heart Failure Induction
3:58
Pressure Overload with Iterative Pulmonary Embolism Induction
4:40
Systemic Hemodynamic Restoration
5:30
Results: Representative Acute Right Heart Failure Phenotype Analyses
7:07
Conclusion
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