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Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

DOI :

10.3791/58455-v

November 8th, 2018

November 8th, 2018

10,780 Views

1Department of Medical Sciences, Section of Pharmacology, Neuroscience Center, University of Ferrara and National Institute of Neuroscience

Here, we describe a method for in vivo microdialysis to analyze aspartate and glutamate release in the ventral hippocampus of epileptic and non-epileptic rats, in combination with EEG recordings. Extracellular concentrations of aspartate and glutamate may be correlated with the different phases of the disease.

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