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Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

DOI :

10.3791/58744-v

April 12th, 2019

April 12th, 2019

5,899 Views

1State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University

This article presents a detailed protocol for T4 ligation and denaturing PAGE purification of small circular DNA molecules, annealing and native PAGE analysis of circular tiles, assembling and AFM imaging of 1D and 2D DNA nanostructures, as well as agarose gel electrophoresis and centrifugation purification of finite DNA nanostructures.

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Stable DNA Motifs

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