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Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

DOI :

10.3791/60531-v

February 9th, 2020

February 9th, 2020

10,991 Views

1Molecular Oncology Center, Hospital Sírio-Libanês

Here, we describe a simple and inexpensive method that allows the quantification of adhesive tumor cells to lymph node (LN) cryosections. LN-adherent tumor cells are readily identified by light microscopy and confirmed by a fluorescence-based method, giving an adhesion index that reveals the tumor cell-binding affinity to LN parenchyma.

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Tumor Cell Adhesion

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