JoVE Logo
Faculty Resource Center

Sign In

Characterization of Cell Membrane Extensions and Studying Their Roles in Cancer Cell Adhesion Dynamics

DOI :

10.3791/56560-v

March 26th, 2018

March 26th, 2018

7,287 Views

1Department of Surgery & Yale Endocrine Neoplasia Laboratory, Yale University School of Medicine, 2Yale New Haven Hospital

This study demonstrates the utility and ease of quantitative cell membrane extension measurement and its correlation to adhesive capacity of cells. As a representative example, we show here that Dickkopf-related protein 3 (DKK3) promotes increased lobopodia formation and cell adhesiveness in adrenocortical carcinoma cells in vitro.

Tags

Cell Membrane Extensions

-- Views

Related Videos

article

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG)

article

Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization

article

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

article

Mesenchymal Stem Cell Isolation from Pulp Tissue and Co-Culture with Cancer Cells to Study Their Interactions

article

Flow Cytometric Analysis of Mitochondrial Reactive Oxygen Species in Murine Hematopoietic Stem and Progenitor Cells and MLL-AF9 Driven Leukemia

article

Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines

article

Semi-automatic PD-L1 Characterization and Enumeration of Circulating Tumor Cells from Non-small Cell Lung Cancer Patients by Immunofluorescence

article

Radiosensitivity of Cancer Stem Cells in Lung Cancer Cell Lines

article

Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane

article

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved