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Measurement of Natural Killer Cell-Mediated Cytotoxicity and Migration in the Context of Hepatic Tumor Cells

DOI :

10.3791/60714-v

6:55 min

February 22nd, 2020

February 22nd, 2020

17,419 Views

1Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham

Evasion of natural killer (NK) cell-mediated eradication by cancer cells is important for cancer initiation and progression. Here, we present two non-radioactivity-based protocols to evaluate NK cell-mediated cytotoxicity toward hepatic tumor cells. Additionally, a third protocol is presented to analyze NK cell migration.

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Keywords NK Cell Function

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