Real-Time Intravital Multiphoton Microscopy to Visualize Focused Ultrasound and Microbubble Treatments to Increase Blood-Brain Barrier Permeability
4.2K Views
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06:29 min
•
February 5th, 2022
DOI :
February 5th, 2022
•Charissa Poon1,2, Melina Mühlenpfordt*3, Marieke Olsman*3, Spiros Kotopoulis4,5, Catharina de Lange Davies3, Kullervo Hynynen1,2,6
1Physical Sciences Platform, Sunnybrook Research Institute, 2Institute of Biomedical Engineering, University of Toronto, 3Department of Physics, Norwegian University of Science and Technology, 4Department of Clinical Medicine, University of Bergen, 5Exact Therapeutics AS, 6Department of Medical Biophysics, University of Toronto
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Chapters in this video
0:07
Introduction
1:18
Material Preparation
1:46
Animal Preparation
3:26
Placement of the Ring Transducer
4:05
Multiphoton Microscopy Imaging
4:30
Ultrasound Exposure
4:56
Representative Results
5:52
Conclusion
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