Surgical Preparations and Tracheotomy and Mechanical Ventilation
2:24
Aortic Debanding
4:06
Tracheal Extubation and Post-Operative Care
5:19
Results: Analysis of Aortic Blood Flow, Ventricular Function, and Hemodynamics after Debanding Surgery
7:09
Conclusion
Transcript
Our protocol describes a surgical procedure to remove ascending aortic banding in a rat model of pulmonary hypertension due to left heart disease, which leads to the reversal of pulmonary hypertension. This technique presents a valuable tool to st
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The present protocol describes a surgical procedure to remove ascending-aortic banding in a rat model of pulmonary hypertension due to left heart disease. This technique studies endogenous mechanisms of reverse remodeling in the pulmonary circulation and the right heart, thus informing strategies to reverse pulmonary hypertension and/or right ventricular dysfunction.