Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
2.2K Views
•
13:41 min
•
January 13th, 2023
DOI :
January 13th, 2023
•Claire Wunker1,2, Karolina Piorkowska3, Ben Keunen3, Yael Babichev2, Suzanne M. Wong3,4, Maximilian Regenold5, Michael Dunne5, Julia Nomikos1,2, Maryam Siddiqui6, Samuel Pichardo6, Warren Foltz7, Adam C. Waspe3,8, Justin T. Gerstle3,9, James M. Drake1,3,4,10, Rebecca A. Gladdy1,2,10
1Institute of Medical Science, University of Toronto, 2Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 3The Wilfred and Joyce Posluns Centre for Image-Guided Innovation and Therapeutic Intervention, The Hospital for Sick Children, 4Institute of Biomedical Engineering, University of Toronto, 5Leslie Dan Faculty of Pharmacy, University of Toronto, 6Departments of Radiology and Clinical Neurosciences, University of Calgary, 7Department of Radiation Oncology, University of Toronto, 8Department of Medical Imaging, University of Toronto, 9Department of Pediatric Surgery, University of Toronto, 10Department of Surgery, University of Toronto
Chapters in this video
0:04
Introduction
1:11
Intramuscular Cell Injection
2:08
Screening MRI Scan and HIFU Treatment
10:46
Results: Average Temperatures and Success Rates of Hyperthermia Treatment and Doxorubicin Levels in the Tumor
13:03
Conclusion
Related Videos
14:10
Contrast Ultrasound Targeted Treatment of Gliomas in Mice via Drug-Bearing Nanoparticle Delivery and Microvascular Ablation
15.9K Views
10:48
PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
9.4K Views
07:56
Protocol for Long Duration Whole Body Hyperthermia in Mice
11.5K Views
07:47
Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance
9.0K Views
09:10
An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of Glioblastoma
319 Views
09:01
Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
3.0K Views
09:07
Sonodynamic Therapy for the Treatment of Glioblastoma Multiforme in a Mouse Model Using a Portable Benchtop Focused Ultrasound System
2.3K Views
05:08
Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model
6.1K Views
Real-Time Magnetic Resonance Guided Focused Ultrasound for Painful Bone Metastases
1.7K Views
06:45
In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System
4.2K Views
Copyright © 2025 MyJoVE Corporation. All rights reserved