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In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function

DOI :

10.3791/59275-v

8:04 min

February 27th, 2019

February 27th, 2019

10,865 Views

1Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, City of Hope Beckman Research Institute and Medical Center, 2Irell and Manella Graduate School of Biological Sciences, City of Hope Beckman Research Institute and Medical Center

Here, we describe an in vitro co-culture method to recursively challenge tumor-targeted T cells, which allows for phenotypic and functional analysis of antitumor T cell activity.

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In Vitro Tumor Cell Rechallenge

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