JoVE Logo

登录

Chapter 1

Pharmacokinetics and Pharmacodynamics: Introduction

生物药剂学和药代动力学:概述
生物药剂学和药代动力学:概述
Drugs come in various dosage forms, including solids, liquids, semisolids, or aerosols. These formulations deliver drugs at the site of action, triggering ...
药代动力学模型:概述
药代动力学模型:概述
Pharmacokinetic models use mathematical analysis to express a drug's time course in the body. These models can simulate rates of a drug's ...
药物浓度与时间相关性
药物浓度与时间相关性
Plasma drug levels, plotted at regular intervals, help track its time course in the body. For instance, consider a plot after a single oral dose. The drug ...
药物浓度:测量
药物浓度:测量
Drug concentration represents the drug amount present in a biological sample. It helps assess the initial drug pharmacokinetics in the body. The samples ...
药代动力学:药代动力学中的基本数学原理:微积分和图形
药代动力学:药代动力学中的基本数学原理:微积分和图形
Pharmacokinetic models view drugs within the body as dynamic entities and rely on calculus as a vital tool for quantitative drug movement analysis. ...
药代动力学中的基本数学原理:数学表达式和单位
药代动力学中的基本数学原理:数学表达式和单位
Mathematical expressions help understand pharmacokinetic parameters by using equations to describe the relationships between different variables. For ...
药代动力学中的基本数学原理:反应速率和顺序
药代动力学中的基本数学原理:反应速率和顺序
Pharmacokinetic models incorporate reaction order and rate to comprehend processes such as drug absorption and elimination. In pharmacokinetics, the rate ...
群体药代动力学数据分析
群体药代动力学数据分析
Traditional pharmacokinetic methods involve taking multiple samples from a few individuals and estimating pharmacokinetic parameters. Despite their common ...
药效学:概述和原理
药效学:概述和原理
Pharmacodynamics is the scientific study that explores the biochemical, cellular, and physiological effects of drugs on the body. Most drug effects result ...
结构-活性关系和药物设计
结构-活性关系和药物设计
Drug design involves discovering new medications based on specific biological targets. It relies on structure-activity relationships, SAR, or quantitative ...
激动和拮抗:量化
激动和拮抗:量化
Administration of drugs can lead to either agonist or antagonist effect. Agonism occurs when a drug activates a receptor, triggering a biological ...
药物管制治理:监管机构及其影响
药物管制治理:监管机构及其影响
Drug control governance involves global regulatory bodies that standardize and control the safety and efficacy of pharmaceuticals, as well as prevent ...
JoVE Logo

政策

使用条款

隐私

科研

教育

关于 JoVE

版权所属 © 2025 MyJoVE 公司版权所有,本公司不涉及任何医疗业务和医疗服务。