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JoVE Journal

Medicine

This content is Open Access.

Mouse Model of Intraluminal MCAO: Cerebral Infarct Evaluation by Cresyl Violet Staining

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09:40 min

November 6th, 2012

November 6th, 2012

62,601 Views

0:05

Title

1:46

Animals

2:03

Monofilaments

2:16

Surgical Procedure

4:59

Restoration of Middle Cerebral Artery (MCA) Blood Flow

5:57

Neuroscore

6:51

Cresyl Violet Staining

7:53

Results

9:06

Conclusion

The intraluminal middle cerebral occlusion model in mice is herein presented. The extent of cerebral infarct is evaluated by a neurologic score and cresyl violet staining, an alternative staining to TTC, offering the great advantage to test in parallel many interest markers.

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