Osteoclast Differentiation and Cancer Cell Co-culture
4:06
Results: Representative Effects of Everolimus on Osteoclastogenesis Treatment
4:51
Conclusion
Transkript
The overall goal of this in vitro human preclinical model of osteoclastogenesis derived from peripheral blood monocytes, or PBMCs, cultured with breast cancer cell lines is to mimic cancer cell osteoclast interactions. This method can help to answ
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This protocol describes development of an in vitro human preclinical model of osteoclastogenesis from peripheral blood monocytes cultured with breast cancer cell lines to mimic the cancer cell-osteoclast interaction. The model could be used to further our understanding of bone metastasis formation and improve therapeutic options.