Results: Measurement of the Microstructural Changes in Adventitial Collagen and the Internal Elastic Lamina in Response to Vessel Pressure
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Conclusion
Transkript
The overall goal of this methodology is to provide a standardized procedure for obtaining images of live human resistance arteries for analysis of the relationship between the microarchitecture of the extracellular matrix and the mechanics of the
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We describe simultaneous mechanical testing and 3D-imaging of the arterial wall of isolated, live human resistance arteries, and Fiji and Ilastik image analyses for the quantification of elastin and collagen spatial organization and volume densities. We discuss the use of these data in mathematical models of arterial wall mechanics.