Surgical Subcutaneous Tumor Fragment Implantation and Serial and End Point Assessment
5:35
Results: Representative Serial Radiography
6:14
Conclusion
Transkript
This study allows for flexibility in creating primary bone tumors or bone metastasis by placing solid tumor grafts into bone. This technique is a departure from injecting tumor cell suspensions in the bone. This method overcomes the limitation of
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Bone metastasis models do not develop metastasis uniformly or with a 100% incidence. Direct intra-osseous tumor cell injection can result in embolization of the lung. We present our technique modeling primary bone tumors and bone metastasis using solid tumor graft implantation into bone, leading to reproducible engraftment and growth.