Results: Combining Olaparib with Temozolomide Enhances DNA damage in Glioma Cells
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Conclusion
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The overall goal of this experiment is to investigate the effectiveness of genotoxic agents in cancer cells using a single cell electrophoresis assay, which is also called the comet assay. This procedure is a sense to measure the four genetic toxi
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The comet assay is an efficient method to detect DNA damage including single and double-stranded DNA breaks. We describe alkaline and neutral comet assays to measure DNA damage in cancer cells to evaluate the therapeutic effect of chemotherapy.