Preparing the PDMS Mold for Cell or Tissue Culture
5:30
Casting Collagen and Fibrin Hydrogel Tissues
7:25
Results: Mold Enhanced Alignment of Cardiac Tissue Constructs
8:22
Conclusion
Transcribir
This method can facilitate research in the tissue-engineering field related to tissue development, cell alignment, and mechanical analysis of polymers and engineered tissues. The main advantage of this technique is that it is low-cost, easy to use
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Herein we present a rapid, facile, and low-cost method for fabricating custom polydimethylsiloxane molds that can be used for producing hydrogel-based engineered tissues with complex geometries. We additionally describe results from mechanical and histological assessments conducted on engineered cardiac tissues produced using this technique.