Preparation of Reagents and Supplies for Glove Box Usage
2:16
Microwave Irradiation
3:03
Product Isolation
5:32
Results: 1H and 13C NMR Spectra and Flash Chromatography Purification Plot
6:33
Conclusion
Transcripción
This protocol utilizes microwave irradiation and a palladium catalyst to attach a heteroaryl fragment directly on the alpha carbon of a ketone. The main advantage of this technique is the rapid construction of a heteroaryl compound for medicinal c
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Heteroaryl compounds are important molecules utilized in organic synthesis, medicinal and biological chemistry. A microwave-assisted heteroarylation using palladium catalysis provides a rapid and efficient method to attach heteroaryl moieties directly to ketone substrates.