January 16th, 2015
•The goal of this protocol is to provide automated methods to quantify chronic lung pathologies in a murine model of COPD. The protocol includes exposing mice to cigarette smoke (CS), measuring pulmonary function, inflating the lungs, and using morphometry methods to measure emphysema and small airway remodeling in mice.
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Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
Protocol for Long Duration Whole Body Hyperthermia in Mice
In vivo Measurement of the Mouse Pulmonary Endothelial Surface Layer
Echocardiographic Assessment of the Right Heart in Mice
Automated Measurement of Microcirculatory Blood Flow Velocity in Pulmonary Metastases of Rats
An Improved Method for Rapid Intubation of the Trachea in Mice
A Model of Cardiac Remodeling Through Constriction of the Abdominal Aorta in Rats
Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals
Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice