September 26th, 2019
•Presented here is a useful protocol for lung fixation that creates a stable condition for histological evaluate of lung specimens from a mouse model of emphysema. The main advantage of this model is that it can fix many lungs with the same constant pressure without lung collapse or deflation.
Vidéos Connexes
Pressure Controlled Ventilation to Induce Acute Lung Injury in Mice (Video) | JoVE
Improved Visualization of Lung Metastases at Single Cell Resolution in Mice by Combined In-situ Perfusion of Lung Tissue and X-Gal Staining of lacZ-Tagged Tumor Cells (Video) | JoVE
Automated Measurement of Pulmonary Emphysema and Small Airway Remodeling in Cigarette Smoke-exposed Mice (Video) | JoVE
Cardiac Catheterization in Mice to Measure the Pressure Volume Relationship: Investigating the Bowditch Effect (Video) | JoVE
Instillation and Fixation Methods Useful in Mouse Lung Cancer Research (Video) | JoVE
Evaluation of Lung Metastasis in Mouse Mammary Tumor Models by Quantitative Real-time PCR (Video) | JoVE
Ultrasound-based Pulse Wave Velocity Evaluation in Mice (Video) | JoVE
An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice (Video) | JoVE
A Minimally Invasive Model to Analyze Endochondral Fracture Healing in Mice Under Standardized Biomechanical Conditions (Video) | JoVE
Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice (Video) | JoVE